An Italian American still living with his mom decides to cure his overeating before things get too bad, and his cousin soon joins him to lose weight together.
Chad's weight of 700 pounds has become not only difficult to manage but extremely dangerous for his health, so he decides to undergo gastric bypass surgery.
A woman weighing at 600 pounds feels she can't contribute to her marriage, leading her to get weight loss surgery, but her entire world changes afterwards.
Diana weighs 620-pounds and is desperate to overcome her food addiction, which leads her to follow the lead of her niece to embark on a weight loss journey.
Gina hopes to lose weight and save her marriage by undertaking Dr. Now's strategy when he mother and sister blame her wife for exacerbating her weight problem.