The season starts off with problems for several ships and their crews as one gets caught on a sandbar and another loses a huge catch to mechanical failures.
A captain calls his eleven-year-old son to come onboard for luck which seems to work as they make a catch so big they struggle getting back to the dock.
Dr. Oakley has to castrate a yak bull that's not taking to the anesthesia, and then she needs to sedate a lynx with a second cat nearby being a distraction.
Dr. Oakley is busy at the Yukon Wildlife Preserve treating a caribou that has fast-growing, giant warts on its face and a mountain goat with a mangled foot.
Dr. Oakley celebrates spring by helping a caribou fight the heat, delivering a weak cow's oversized calf and saving a horse by removing it's infected eye.
Dr. Oakley uses the Alaska Wildlife Conservation Center to test wild elk for disease and finds herself pushed to the limit attempting to neuter a wolverine.
As summer gets into full swing, Dr. Oakley treats a sled dog that has porcupine quills in its face and eyeball; the vet's daughter helps rescue a bald eagle.