The team faces political difficulties after four terrorists are shot and one kidnapped in New York, with no official record of them arriving in the country.
Special Agents Maggie Bell and OA Zidan pursue an active sniper who is out on a killing spree with no apparent motive to explain their violent outburst.
Team Scorpion must rely on the assistance of a problematic former member of the group when they are tasked with repairing a Los Angeles nuclear reactor.
Team Scorpion turns to a musical artist for help after he develops an algorithm that can produce popular songs which will pin the killer of a music blogger.
Team Scorpion helps protect Agent Cabe's ex-wife after she stumbles across some incriminating evidence that hints at foul play in the death of a congressman.
The BAU is asked to help the Centers for Disease Control when they believe that a series of mysterious deaths in Virginia could be the act of bioterrorism.
A series of mummified remains from multiple victims are found inside an elderly couple's home; Rossi attempts to reestablish a connection with his ex-wife.
A movie theater is leveled in the aftermath of a natural gas explosion, which the team learns was caused by a hacker who could trigger further explosions.
Pride is unable to rely on the team's support and faces a seemingly inescapable situation when the Eddie Barrett investigation reveals a sinister plot.
The FBI races to find the kidnapped daughter of a senator who is being held for ransom, and they must uncover the senator's past to unravel who did this.