Paladin accidentally takes the wrong road during a storm and ends up stranded in a wild frontier town, where he is accused of murder by a corrupt sheriff.
Cheyenne's past relationship with a woman comes back to haunt him when it gets him involved in a blackmailing scheme that nearly gets him beaten to death.
After the Stryder Gang is rounded up and thrown in the jail, they hatch a plan and manage to escape from confinement, so Heath and Nick try to help catch them.
A hard and ruthless man takes on a job as a stage line superintendent, and is desperate to get Jess Harper fired on way or another; Slim is alarmed by theft.
Hale is entrusted with delivering a box containing $8,000 to a bank, but another man who has stowed himself along the wagon train is determined to steal it.
Bill Hawks travels to a small settlement in the desert to visit old American Indian friend at his ranch, but he soon discovers that his friend has gone missing.
A deadly epidemic strikes Dodge City, and Marshal Dillon sets up a temporary hospital in the jail, where Kitty and her girls take care of the patients.
The men of Dodge City become intimated by an Amazonian visitor, who defies the gender rules of the land by fighting and using improper language like men.
A man arrives at Sherman Ranch and Relay Station with his new wife, and finds that he is a new Marshal in Laramie as the Torrey Brothers killed their Marshal.
A prominent German pianist's beloved piano is stolen and held for ransom just before he scheduled to give a concert for a now-wealthy former saloon hostess.
After a vicious murderer escapes from prison, he seeks revenge against his traitorous wife, who aided in his capture, and Paladin, who brought him to prison.
A frightened boy is left alone to die in the wilderness after witnessing a fellow traveler kill his father, and he tries to get revenge for his father's death.
After the Virginian is involved in an altercation in which he is forced to kill his opponent, the victim's father asks him to search for an estranged daughter.