A former colleague of Dr. Quest's is breeding a species of oversized carnivorous lizards, and when the Quests visit him, they become prey for the reptiles.
Dr. Quest is summoned by the residents of an exotic island to investigate a suspiciously erupting volcano, and he finds the eruptions are unnaturally caused.
Thundarr aids a group of humans that are fighting off a wizard with the use of a machine, but are forced to travel through time to fix it when it malfunctions.
Foghorn and a cat get into a debacle over a worm that Leghorn is chasing; Foghorn wants to eat the worm, but the cat wants the worm for bait to catch fish.
Tom serves a royal kitten in hopes of winning her heart, but he fails to get her attention; Droopy encounters a mad scientist; Tom and Jerry in a unique class.
The Tasmanian Devil manages to escape from the zoo and ends up on Bugs and Daffy's doorstep, where Daffy is terrified of him, but Bugs adopts him as his pet.
Lola takes Bugs on a trip to Paris in hopes that they will fall in love; while sweeping Granny's attic, Daffy learns that she was once a spy in World War II.
Fred and Barney decide to buy a sweepstakes ticket without telling their wives, but when they hide the ticket too well, it becomes a scramble to get it back.
When Fred learns 'The Adventures of Sassie' is auditioning animal talent he coaches Dino extensively and takes him to the tryouts, where he lands a part.
Popeye and Bluto compete to see who can build a battleship the fastest to secure a government contract that will allow their shipyard to build an entire fleet.
Popeye's commander orders him to stand at attention as a mild punishment for his antics, but trouble arises when enemy troops suddenly attack the ship.
Bluto tricks Popeye as they swap uniforms so that Bluto can sneak off the military base, and as a result, Popeye winds up having to do Army-related drills.
Dr. Quest has been working on a new undersea vehicle commissioned by the government, but foreign agents hijack the machine with Jonny and Race on board.
After a distress call from a colleague, the Quest team travels to a remote island to find that he has created a powerful, destructive and invisible creature.