The Professor develops a revolutionary new invention which allows people to exchange brains, leading him and Amy to swap minds as a part of an agreement.
Three nerdy high schoolers go to great lengths to obtain liquor for a party in the hopes of impressing their would-be girlfriends before they leave for college.
Moe goes into business creating homemade whiskey; Bart has to take care of Grampa after he is injured; Lisa is upset about a hologram of Bleeding Gums Murphey.
When Homer, Lenny, Moe, and Carl win $200,000 in the Springfield Lottery, Carl runs off to Iceland with the winnings, leading the others to follow him.
Marge meets up with a man after accidentally visiting a website dedicated to arranging affairs for married people instead of a site dedicated to cupcakes
A rhyming Homer wreaks havoc as he endeavors in a twist on the tales of Dr. Seuss; a beheaded Bart must share Lisa's body; Mr. Burns' traveling circus.
Following the death of a neighbor, Homer, Marge, Mr. Burns and Kent Brockman attempt to right their past wrongs as they remember their worst decisions.
Homer joins the "You-Only-Live-Once" spirit when Marge pushes him into having a former pen pal of his stay over at the house as they tackle an old "to-do" list.
Gene and Courtney are given the opportunity to be the new hosts of morning announcements, but their romantic history poses challenges; Tina's plan goes awry.
Tina volunteers to work with Nurse Liz, and ends up being a part of a lice-infestation; Bob tries to improve the restaurant but ends up driving customers away.
The Belcher kids hop into action after news of a bounce house crisis at a birthday party; Bob encounters a guest at the restaurant, forcing him to face a fear.
After learning of a nearby mystical creature, Gene takes the Belcher kids on a quest to find it; during a slow day at the restaurant, Linda becomes competitive.
Joe becomes a media darling, after Peter spikes his sports drink with steroids during track and field event for the disabled; the kids bicker over $26.
Brian is sentenced to community service following a drunk driving episode; Peter cares for three endangered nestlings living in his freshly-grown beard.
When Brian shows interest in theatre, Lois convinces him to try out for School of Performing Arts, but during the audition, Brian is dismissed by the judges.
Peter wishes for a Jewish accountant to help his family with its ample economic problems and after meeting Max Weinstein, decides to convert Chris to Judaism.
Peter discovers a copy of "Passion of the Christ 2" in Mel Gibson's suite while on a hectic second honeymoon with Lois; Stewie and Brian babysit Meg and Chris.
Lois and Peter are shocked to find a murderous note written to Chris by a sexy new teacher; Brian subs at the school, after one of the faculty wins the lottery.
After an encounter with a mysterious four-dimensional space whale, Leela finds herself becoming obsessed with hunting down and harpooning the elusive creature.
In a local softball league, Thaterton stacks his team with pro athletes, leading Hank to pull Peggy off her team to serve as Strickland Propane's ace pitcher.