The villain gang comprised of criminals like Harley Quinn, Bloodsport, and Peacemaker join a top-secret, suspicious task force and get dropped off on an island.
Lilly and Scotty re-open a case involving a young woman who emerges from a coma with no memory of the murder of her daughter who mysteriously fell to her death.
The Charmed Ones align themselves with a demon as they seek to restore their reputations and race Billie and Christy to the source of the greatest power known.
Piper and Billie depart each other's lives after tragic and devastating losses, and Piper asks for Coop's help to travel back in time and set things right.
Sam becomes curious about Dean's life when he learns that his brother was sent to the same delinquent home that they are visiting for an old buddy of Dean's.
Upon receiving a call from Sheriff Mills, Sam and Dean check out a series of murders linked to a church group, but events take a turn when Dean goes missing.
While Sam and Dean investigate an angel slaughtering, Castiel is seized and tormented; Dean, conflicted by Ezekiel's demands, questions if he should tell Sam.
Following the aftermath of losing Kevin, Dean must turn to Crowley for help in exorcising Sam of Gadreel by separating his brother's brain from the angel's.
An assassin wants to do his job peacefully in the wake of several disasters, but trouble arises during his current mission on the world's fastest train.
A decade after his wife and child are brutally murdered, a man intends to exact revenge on everyone who was involved in allowing one of the killers to go free.